Structure-based Drug Discovery
Structure-based Drug Discovery
Product Details
Book Publisher: Springer (21 February, 2007)
ISBN: 1402044062
Book author: Harren Jhoti, Andrew Leach
Book Description:
Discovering new medicines is becoming more challenging & the pharmaceutical industry is looking into new technologies into help in this mission. Structure-based drug discovery methods have been transformed in the last 5-10 years & are at present having a major impact on the discovery of new drugs. Some of the most exciting developments in the field, such as Fragment-based methods, are described in this book.
The book describes the latest developments in technologies that can be used into obtain the 3-D structures including the high profile structural genomics approaches being utilised worldwide. The use of 3-D protein structures in new, Fragment-based, approaches into drug discovery are described in some detail. This book includes experimental approaches using X-ray crystallography & NMR for
Fragment-based screening as we as other biophysical methods for studying protein/ligand interactions. In addition, developments in computational chemistry methodology are covered together with an assessment of practical applications.
This book is an invaluable resource for medicinal chemists in industry, computational chemists, drug discovery scientists & postgraduates in chemistry or structural biology.
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Tags: pharmaceutical textbooks, Pharmacology medical book, Structure-based Drug Discovery, [amtap book:isbn=1402044062]
